1.Product description
Estrone (E1, and also oestrone) is an estrogenic hormone secreted by the ovary as well as adipose tissue with the chemical name of 3-hydroxyestra-1,3,5(10)-triene-17-one and the chemical formula C18H22O2. Estrone is an odorless, solid crystalline powder, white in color with a melting point of 254.5°C and a specific gravity of 1.23. Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy.
Estrone is known to be a carcinogen for human females as well as a cause of breast tenderness or pain, nausea, headache, hypertension, and leg cramps in the context of non-endogenous exposure. In men, estrone has been known to cause anorexia, nausea, vomiting, and erectile dysfunction. Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women.
Estrone was discovered and isolated by German chemist Adolf Butenandt.
Basic Info
Chemical Name | estrone |
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Synonyms | Femidyn; Estrin; Estra-1,3,5(10)-trien-17-one, 3-hydroxy-; 3-Hydroxy-1,3,5(10)-estratrien-17-one; Estrone; Expand |
CAS No. | 53-16-7 |
Molecular Formula | C18H22O2 |
Molecular Weight | 270.36600 |
PSA | 37.30000 |
LogP | 3.81740 |
Properties
Appearance & Physical State | White crystalline powder |
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Density | 1.164 g/cm3 |
Boiling Point | 445.2ºC at 760 mmHg |
Melting Point | 258-261ºC |
Flash Point | 189.7ºC |
Refractive Index | 165 ° (C=1, Dioxane) |
Water Solubility | 0.03 g/L |
Stability | Stable under normal temperatures and pressures. |
Storage Condition | Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. |
Safety Info
RTECS | KG8575000 |
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Safety Statements | S53-S45 |
HS Code | 2937290090 |
Packing Group | I; II; III |
WGK Germany | 3 |
Risk Statements | R45; R60; R61 |
Hazard Codes | T |
Signal Word | Danger |
Caution Statement | P210; P260; P280; P301 + P310 + P330; P302 + P352 + P312; P370 + P378 |
Symbol | GHS02, GHS06, GHS08 |
Hazard Declaration | H225; H301 + H311 + H331; H370 |
2.Shipping
3.Our service
We offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.
we will try our best to satisfied you:
1. Tailor-made for every customers.
2. Third-party test for the products you demand.
3. Test your counter-samples and produce them for you.
4. Best discount for old customers.
5.24 hours service.
4.FAQ
(1) Will you supply sample for test the quality?
We'd like to offer the sample for the quality test, the shipping cost is brone by customer.
(2) What is the payment term?
We accept Western Union, T/T, Moneygram and so on.
(3) How to delivery by express?
Parcel will be shipped out in 3 working days after payment. Usually we use EMS, DHL, Fedex, TNT and so on.
(4) Is there a discount?
Yes, for large quantity , we will support with the best price.
(5) How to make a order?
Send to inquire to us. We do the offer. Payment vis Western Union, Moneygarm , T/T and so on. Then we will arrange the shipping for you. Next we will give you the Tracking Number.