99% Pure Flutamide Powder NSAID Antiandrogen CAS 13311-84-7

99% Purity Flutamide Powder Non Steroidal Antiandrogen CAS 13311-84-799% Purity Flutamide Powder Non Steroidal Antiandrogen CAS 13311-84-799% Purity Flutamide Powder Non Steroidal Antiandrogen CAS 13311-84-7Product Name: FlutamideSynonyms: TIMTEC-BB SBB006930;N1-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]-2-METHYLPROPANAMIDE;2-METHYL-N-

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99% Purity Flutamide Powder Non Steroidal Antiandrogen CAS 13311-84-7
99% Purity Flutamide Powder Non Steroidal Antiandrogen CAS 13311-84-7
99% Purity Flutamide Powder Non Steroidal Antiandrogen CAS 13311-84-7

Product Name: Flutamide
Synonyms: TIMTEC-BB SBB006930;N1-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]-2-METHYLPROPANAMIDE;2-METHYL-N-(4'-NITRO-3'-(TRIFLUOROMETHYL)PHENYL)PROPANAMIDE;2-METHYL-N-(4-NITRO-3-[TRIFLUOROMETHYL]PHENYL)PROPANAMIDE;FLUTAMIDE;AURORA KA-860;2-Methyl-N-[4-nitro-3-(trifluoromethyl)-phenyl]-propionamide;Flutamide USP25
CAS: 13311-84-7
MF: C11H11F3N2O3
MW: 276.21
EINECS: 236-341-9
Appearance: Light Yellow Powder
Uses: Antiandrogen; antineoplastic (hormonal).
Uses: neuroleptic
Uses: Flutamide is a nonsteroidal antiandrogen drug; antineoplastic (hormonal).
Uses: Besides prostate cancer, flutamide has also been tested and/or used off-label in other hyperandrogenism-related disorders like benign prostatic hyperplasia, acne vulgaris, and hirsutism syndrome. Due to its teratogenic potential, flutamide is restricted for premenopausal women and used only in combination with effective contraception.

Flutamide is a kind of synthetic, non-steroidal antiandrogen which is mainly used for the treatment of prostate cancer. It is a kind of toluidine derivative and a nonsteroidal antiandrogen with a similar structure of bicalutamide and nilutamide. The mechanism of its anti-cancer property is through acting as a selective antagonist of the androgen receptor (AR), preventing androgens such as testosterone and its active metabolite dihydrotestosterone from binding to ARs in the prostate gland. This process inhibits androgen-dependent DNA and protein synthesis in the tumor cell. Therefore, it can prevent androgens from stimulating the growth of prostate cancer cells. Moreover, it can also be used for the treatment of hyperandrogenism in women. It is quite effective in alleviating symptoms such as acne, seborrhea, hirsutism and androgenetic alopecia. Finally, it is also useful as a component in the transgender hormone therapy.


99% Purity Flutamide Powder Non Steroidal Antiandrogen CAS 13311-84-7

99% Purity Flutamide Powder Non Steroidal Antiandrogen CAS 13311-84-7

 

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